I don’t have access to a licensed cloud v4 node to confirm, but you should be able to configure Dynatrace using the custom environment variables documented at: https://github.com/mendix/cf-mendix-buildpack#dynatrace
DT_PAAS_TOKENThe token for integrating your Dynatrace environment with Cloud Foundry. You can find it in the deploy Dynatrace section within your environment.
DT_SAAS_URLMonitoring endpoint url of the Dynatrace service
DT_TENANTYour Dynatrace environment ID is the unique identifier of your Dynatrace environment. You can find it in the deploy Dynatrace section within your environment.
For full list of options see https://github.com/mendix/cf-mendix-buildpack/blob/master/buildpack/dynatrace.py#L8
Please note that Dynatrace integration is pretty generic. It can monitor OS, DB, JVM and Jetty metrics. But nothing specific to Mendix runtime yet.