Anything is possible, but i do not know of an easy solution here. Mendix is not sharepoint or teams.
We had a similar requirement for Word documents a few years ago and solved it adding a macro to Word, that changes the behaviour of the save button. It no longer saved the file as usual, but calls a web service published by our Mendix app. A happy client, but it was tricky to implement.
I am curious if someone else here has a better solution.